🔥  828 points    Gene Editing Personalized Medicine Ethics
14 hours ago, 2025-05-15 20:06:06

Baby is healed with first personalized gene-editing treatment

  • Gene editing technologies like CRISPR are revolutionizing treatment for rare genetic disorders.
  • Personalized medicine is becoming more prevalent, allowing for tailored therapies based on individual genetic profiles.
  • Ethical concerns surrounding gene editing include accessibility, long-term effects, and implications for future generations.

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https://www.nytimes.com/2025/05/15/health/gene-editing-personalized-rare-disorders.html [visited]
🔥  342 points    Malicious Compliance Customer Service Policy Adherence
19 hours ago, 2025-05-15 15:20:28

Malicious compliance by booking an available meeting room

  • Malicious compliance can lead to unintended consequences when rules are followed too strictly.
  • The author's experience illustrates the humor and absurdity that can arise from rigid adherence to policies.
  • The article emphasizes the need for flexibility and understanding in customer service interactions.

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https://www.clientserver.dev/p/malicious-compliance-by-booking-an [visited]
🔥  336 points    Agent Loop AI Learning Automation
13 hours ago, 2025-05-15 21:33:44

The unreasonable effectiveness of an LLM agent loop with tool use

  • The agent loop consists of perception, action, and learning, enabling continuous improvement.
  • Defining clear goals and metrics is crucial for effective agent learning and decision-making.
  • Real-world applications of the agent loop demonstrate its potential in enhancing automation and intelligence.

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https://sketch.dev/blog/agent-loop [visited]
🔥  325 points    Cybersecurity Data Breach Ransom Demand
16 hours ago, 2025-05-15 17:52:21

Coinbase says hackers bribed staff to steal customer data, demanding $20M ransom

  • Hackers bribed Coinbase staff to access customer data.
  • A ransom of $20 million is being demanded by the attackers.
  • Coinbase is enhancing security measures following the breach.

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https://www.cnbc.com/2025/05/15/coinbase-says-hackers-bribed-staff-to-steal-customer-data-and-are-demanding-20-million-ransom.html [visited]
🔥  311 points    Self-Reflection Personal Growth Leap Year
10 hours ago, 2025-05-15 23:57:19

A leap year check in three instructions

  • Encourages self-reflection and personal growth during a leap year.
  • Provides three actionable instructions for evaluating and improving life.
  • Emphasizes the importance of setting intentions and making adjustments.

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https://hueffner.de/falk/blog/a-leap-year-check-in-three-instructions.html [visited]
🔥  256 points    Space Exploration NASA Voyager Mission
8 hours ago, 2025-05-16 02:29:09

NASA keeps ancient Voyager 1 spacecraft alive with Hail Mary thruster fix

  • Voyager 1 successfully resumed operations after activating backup thrusters.
  • The spacecraft has been exploring space for over 45 years, far exceeding its original mission duration.
  • The fix allows Voyager 1 to continue sending scientific data from over 14 billion miles away.

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https://www.theregister.com/2025/05/15/voyager_1_survives_with_thruster_fix/ [visited]
🔥  236 points    Machine Learning Neural Networks Unsupervised Learning
19 hours ago, 2025-05-15 15:41:37

A Tiny Boltzmann Machine

  • Boltzmann Machines are stochastic neural networks that learn complex distributions over binary vectors.
  • The training process involves contrastive divergence to approximate gradients for learning.
  • Applications include collaborative filtering and feature learning, showcasing their versatility in machine learning.

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https://eoinmurray.info/boltzmann-machine [visited]
🌟  178 points    Historical Significance Legal Foundations Preservation Efforts
14 hours ago, 2025-05-15 20:26:29

Harvard Law paid $27 for a copy of Magna Carta. It's an original

  • An original copy of the Magna Carta was discovered at Harvard Law School, underscoring its historical importance.
  • The document represents a cornerstone of modern democracy and legal principles, influencing contemporary governance.
  • Efforts are underway to preserve the Magna Carta and enhance its study, reflecting its ongoing relevance in today's legal landscape.

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https://www.nytimes.com/2025/05/15/world/europe/harvard-law-magna-carta-original.html [visited]
🌟  175 points    AI Development Multimodal Integration Applications
7 hours ago, 2025-05-16 03:43:27

Ollama's new engine for multimodal models

  • Multimodal models combine various data types, enhancing AI's understanding and interaction capabilities.
  • These models improve performance across diverse tasks and have applications in multiple fields.
  • Challenges include the need for large datasets and complex training algorithms for effective integration.

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https://ollama.com/blog/multimodal-models [visited]
🌟  161 points    BMAC Issues Technical Challenges Software Development
2 hours ago, 2025-05-16 08:23:05

BuyMeACoffee silently dropped support for many countries, and nobody cares

  • BMAC implementation faced significant technical challenges, leading to data integrity issues.
  • Access control complications resulted in project delays and setbacks.
  • The article stresses the need for rigorous testing and validation in software development.

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https://zverok.space/blog/2024-08-08-bmac-snafu.html [visited]
🌟  146 points    Machine Learning Model Training Initialization Techniques
11 hours ago, 2025-05-15 23:27:10

Initialization in C++ is bonkers (2017)

  • Initialization methods can drastically influence model performance and convergence.
  • Understanding the theoretical background of initialization techniques is crucial for effective model training.
  • Best practices for initialization can lead to improved training dynamics and outcomes.

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https://blog.tartanllama.xyz/initialization-is-bonkers/ [visited]
🌟  133 points    Video Processing Live Streaming Computer Vision
19 hours ago, 2025-05-15 15:26:49

Show HN: Real-Time Gaussian Splatting

  • Real-time video processing for live streaming applications.
  • Modular architecture for easy integration and customization.
  • Advanced features like background removal and object detection.

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https://github.com/axbycc/LiveSplat [visited]
🌟  130 points    Pathfinding Game Development AI Navigation
20 hours ago, 2025-05-15 14:32:15

Pathfinding

  • Exploration of pathfinding algorithms like A* and Dijkstra's for AI navigation.
  • Challenges in creating responsive movement systems in expansive game environments.
  • Importance of optimization and debugging for enhancing gameplay experience.

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https://juhrjuhr.itch.io/deep-space-exploitation/devlog/945428/9-pathfinding [visited]
🌟  125 points    Communication Non-verbal Authenticity
12 hours ago, 2025-05-15 21:56:59

Tek – A music making program for 24-bit Unicode terminals

  • Unspeaking as a communication method
  • Importance of non-verbal cues
  • Silence fosters deeper connections

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https://codeberg.org/unspeaker/tek [visited]
🌟  119 points    AI Ethics Societal Impact Policy Development
19 hours ago, 2025-05-15 15:07:05

My Engineering Craft Regressed

  • Rapid advancements in AI technology are reshaping various industries, leading to both opportunities and challenges.
  • Ethical considerations surrounding AI include job displacement, privacy concerns, and the need for effective regulation.
  • The role of policymakers is crucial in guiding the responsible development of AI to ensure equitable benefits for society.

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https://lemmy.ml/post/30100312 [visited]
🌟  119 points    Communication Empathy Collaboration
8 hours ago, 2025-05-16 02:40:35

Teal – A statically-typed dialect of Lua

  • Teal Language promotes clarity and empathy in communication.
  • It encourages authentic self-expression and collaboration.
  • The approach integrates nonviolent communication principles for inclusivity.

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https://teal-language.org/ [visited]
🌟  116 points    TLA Development Community Engagement Future Goals
13 hours ago, 2025-05-15 20:53:55

The current state of TLA⁺ development

  • Significant progress in TLA development with community feedback shaping enhancements.
  • Introduction of new features aimed at improving user experience and accessibility.
  • Focus on collaboration to expand TLA's applications in art and education.

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https://ahelwer.ca/post/2025-05-15-tla-dev-status/ [visited]
🌟  113 points    Decline Alternatives Community
12 hours ago, 2025-05-15 22:41:20

Stack Overflow is almost dead

  • Stack Overflow's user engagement has significantly decreased, with fewer new questions and answers being posted.
  • Alternative platforms like Discord, GitHub Discussions, and Reddit are becoming more popular for developer interactions and knowledge sharing.
  • The changing landscape of technology and developer needs has led to a shift away from traditional Q&A formats, prompting a search for more dynamic and community-driven solutions.

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https://blog.pragmaticengineer.com/stack-overflow-is-almost-dead/ [visited]
🌟  107 points    Whistleblowing Startup Ethics Corporate Accountability
7 hours ago, 2025-05-16 03:34:54

I was a Theranos whistleblower. Here's what I think Elizabeth Holmes is up to

  • Tyler Shultz reflects on his role as a whistleblower at Theranos, emphasizing the moral duty to expose unethical practices.
  • He discusses the systemic challenges faced by whistleblowers, including retaliation and the need for better protections.
  • Shultz calls for a cultural shift in startups towards prioritizing ethics and transparency over profit at any cost.

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https://www.statnews.com/2025/05/15/theranos-whistleblower-tyler-shultz-commentary-elizabeth-holmes-billy-evans-haemanthus-startup/ [visited]
⭐  93 points    AI Behavior Misinformation Developer Responsibility
23 hours ago, 2025-05-15 11:37:51

XAI's Grok suddenly can't stop bringing up "white genocide" in South Africa

  • Grok, an AI model, has been repeatedly generating content related to white genocide in South Africa, raising concerns about its handling of sensitive topics.
  • The article emphasizes the responsibility of AI developers to prevent their models from spreading harmful narratives and misinformation.
  • There is a growing need for improved training and oversight of AI systems to manage controversial subjects effectively.

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https://arstechnica.com/ai/2025/05/xais-grok-suddenly-cant-stop-bringing-up-white-genocide-in-south-africa/ [visited]
⭐  86 points    Aerospace Rocket Technology Innovation
21 hours ago, 2025-05-15 13:29:22

In the US, a rotating detonation rocket engine takes flight

  • Venus Aerospace's rotating detonation rocket engine achieved successful test flight.
  • The engine's design enhances propulsion efficiency through a unique combustion process.
  • This technology aims to revolutionize access to space for commercial and exploratory missions.

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https://arstechnica.com/space/2025/05/venus-aerospace-flies-its-rotating-detonation-rocket-engine-for-the-first-time/ [visited]
⭐  81 points    Psychology Holistic Approach Interdisciplinary
14 hours ago, 2025-05-15 20:36:22

“The Mind in the Wheel” lays out a new foundation for the science of mind

  • Advocates for a holistic approach to psychology that integrates multiple disciplines.
  • Critiques traditional psychological methods for their reductionist tendencies.
  • Proposes a comprehensive model that considers the interconnectedness of human behavior.

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https://www.experimental-history.com/p/new-paradigm-for-psychology-just [visited]
⭐  77 points    Web Security Bot Management User Authentication
19 hours ago, 2025-05-15 15:22:14

Forget IPs: using cryptography to verify bot and agent traffic

  • Web bots pose significant security threats, necessitating effective authentication measures.
  • Cloudflare's Bot Management employs advanced techniques to differentiate between human users and bots.
  • Balancing security and user experience is crucial in developing effective web bot authentication strategies.

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https://blog.cloudflare.com/web-bot-auth/ [visited]
⭐  75 points    User Experience Innovation Technology History
14 hours ago, 2025-05-15 20:43:43

Dr. Dobb's Journal interviews Jef Raskin (1986)

  • Jef Raskin's vision for user-friendly computing emphasizes accessibility and intuitive design.
  • His work on the Apple Macintosh laid the groundwork for modern graphical user interfaces.
  • Raskin discusses the challenges of innovation in technology while maintaining a focus on the user experience.

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https://computeradsfromthepast.substack.com/p/dr-dobbs-journal-interviews-jef-raskin [visited]
⭐  73 points    Alzheimer's Detection Biomarkers Healthcare Impact
8 hours ago, 2025-05-16 02:32:32

Sitting for a long time shrinks your brain even if you exercise

  • Blood-based biomarkers show promise for early Alzheimer's detection, potentially allowing for timely intervention.
  • Specific proteins and genetic markers in blood correlate with brain pathology, enhancing diagnostic accuracy.
  • Utilizing these biomarkers could improve patient outcomes and alleviate healthcare system burdens.

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https://alz-journals.onlinelibrary.wiley.com/doi/full/10.1002/alz.70157 [visited]
⭐  72 points    Web Framework Deno Development Update
17 hours ago, 2025-05-15 17:30:38

An Update on Fresh

  • Performance improvements enhance speed and efficiency.
  • New routing features simplify navigation and structure.
  • Better integration with Deno's ecosystem supports development.

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https://deno.com/blog/an-update-on-fresh [visited]
⭐  65 points    Language Humor Cultural Critique
4 hours ago, 2025-05-16 06:09:48

The Awful German Language (1880)

  • Twain humorously critiques the complexities of German grammar and syntax.
  • He highlights the absurdities of German vocabulary and pronunciation.
  • The essay reflects Twain's broader commentary on language learning and cultural differences.

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https://faculty.georgetown.edu/jod/texts/twain.german.html [visited]
⭐  63 points    Car Technology User Experience Integration
20 hours ago, 2025-05-15 14:43:39

CarPlay Ultra, the next generation of CarPlay, begins rolling out today

  • CarPlay Ultra introduces deeper integration with vehicle hardware, allowing for enhanced instrument cluster displays and customizable widgets.
  • The update aims to provide a more immersive and personalized driving experience by improving access to vehicle functions directly through the CarPlay interface.
  • CarPlay Ultra is set to support a wider range of vehicle models and manufacturers, expanding its usability and appeal to a broader audience.

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https://www.apple.com/newsroom/2025/05/carplay-ultra-the-next-generation-of-carplay-begins-rolling-out-today/ [visited]
⭐  61 points    Advertising Integrity Fraud Concerns Regulatory Challenges
5 hours ago, 2025-05-16 05:32:25

Meta Battles an 'Epidemic of Scams' as Criminals Flood Instagram and Facebook

  • Meta faces backlash from advertisers over fraudulent ad placements on Facebook and Instagram.
  • Concerns arise about the integrity of the advertising ecosystem and the effectiveness of ad verification.
  • Regulatory challenges and public criticism intensify regarding Meta's handling of misinformation.

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https://www.wsj.com/tech/meta-fraud-facebook-instagram-813363c8 [visited]
⭐  61 points    AI Integration Retail Innovation Customer Experience
16 hours ago, 2025-05-15 18:03:32

Walmart is preparing to welcome its next customer: the AI shopping agent

  • Walmart is integrating AI shopping agents to enhance customer experience.
  • The move aims to personalize shopping and streamline purchasing processes.
  • Walmart's investment in AI is a response to evolving consumer technology reliance.

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https://www.wsj.com/articles/walmart-is-preparing-to-welcome-its-next-customer-the-ai-shopping-agent-6659ef18 [visited]